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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1998-1-12
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pubmed:abstractText |
Four experiments examined effects of quinolinic acid-induced lesions of the anterior cingulate, posterior cingulate, and medial frontal cortices on tests of visual discrimination learning, using a new "touchscreen" testing method for rats. Anterior cingulate cortex lesions impaired acquisition of an 8-pair concurrent discrimination task, whereas posterior cingulate cortex lesions facilitated learning but selectively impaired the late stages of acquisition of a visuospatial conditional discrimination. Medial frontal cortex lesions selectively impaired reversal learning when stimuli were difficult to discriminate; lesions of anterior and posterior cingulate cortex had no effect. These results suggest roles for the anterior cingulate, posterior cingulate, and medial frontal cortex in stimulus-reward learning, stimulus-response learning or response generation, and attention during learning, respectively.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0735-7044
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
920-36
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:9383514-Animals,
pubmed-meshheading:9383514-Association Learning,
pubmed-meshheading:9383514-Attention,
pubmed-meshheading:9383514-Brain Mapping,
pubmed-meshheading:9383514-Conditioning, Classical,
pubmed-meshheading:9383514-Discrimination Learning,
pubmed-meshheading:9383514-Emotions,
pubmed-meshheading:9383514-Frontal Lobe,
pubmed-meshheading:9383514-Gyrus Cinguli,
pubmed-meshheading:9383514-Male,
pubmed-meshheading:9383514-Mental Recall,
pubmed-meshheading:9383514-Motivation,
pubmed-meshheading:9383514-Pattern Recognition, Visual,
pubmed-meshheading:9383514-Psychomotor Performance,
pubmed-meshheading:9383514-Rats,
pubmed-meshheading:9383514-Reaction Time,
pubmed-meshheading:9383514-Reversal Learning
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pubmed:year |
1997
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pubmed:articleTitle |
Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.
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pubmed:affiliation |
Department of Experimental Psychology, University of Cambridge, England.
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pubmed:publicationType |
Journal Article
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