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rdf:type |
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lifeskim:mentions |
umls-concept:C0000925,
umls-concept:C0007961,
umls-concept:C0013714,
umls-concept:C0026649,
umls-concept:C0034655,
umls-concept:C0231530,
umls-concept:C0332256,
umls-concept:C1304649,
umls-concept:C1546426,
umls-concept:C1548280,
umls-concept:C1706211
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pubmed:dateCreated |
1997-11-10
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pubmed:abstractText |
1. Charge movement was studied in the cut twitch fibres of Rana temporaria with a double Vaseline-gap voltage-clamp technique. 2. In fibres containing 0.1 mM EGTA, the I gamma hump component of charge movement was either unresolvable or had a brief duration at all potentials. In the steady-state charge-voltage (Q-V) plots that were separable into the less voltage dependent (Q beta) and more voltage dependent (Q gamma) components, the amount of Q gamma was 0.9 +/- 0.1 nC microF-1. (mean +/- S.E.M., n = 18). 3. Fibres containing 20 mM EGTA showed broad I gamma humps at about -45 mV. The addition of 1.8 mM total Ca2+ to the end-pools accelerated the rising phase and abbreviated the duration of the hump. 4. I gamma in fibres containing 0.1 mM EGTA resembled those in intact fibres when recorded at similar low temperatures. 5. These results explain the controversy concerning the variable appearance of I gamma humps in cut fibres.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-1082506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-16068161,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-1940852,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-2009363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-2212982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-2212983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-2434854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-302416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-3489092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-458722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-6600842,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-6603513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-6975814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-6980275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-7527460,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-8537818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9379411-8741732
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-3751
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
503 ( Pt 3)
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
563-70
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:9379411-Animals,
pubmed-meshheading:9379411-Calcium,
pubmed-meshheading:9379411-Chelating Agents,
pubmed-meshheading:9379411-Cold Temperature,
pubmed-meshheading:9379411-Egtazic Acid,
pubmed-meshheading:9379411-Electric Conductivity,
pubmed-meshheading:9379411-Kinetics,
pubmed-meshheading:9379411-Membrane Potentials,
pubmed-meshheading:9379411-Muscle Contraction,
pubmed-meshheading:9379411-Muscle Fibers, Skeletal,
pubmed-meshheading:9379411-Patch-Clamp Techniques,
pubmed-meshheading:9379411-Rana temporaria
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pubmed:year |
1997
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pubmed:articleTitle |
Charge movement in cut twitch fibres of Rana temporaria containing 0.1 mM EGTA.
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pubmed:affiliation |
Department of Physiology and Biophysics, Indiana University Medical Center, Indianapolis 46202, USA. cshui@hyrax.iupui.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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