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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1997-11-12
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pubmed:abstractText |
Y-chromosomal microsatellites have been investigated for the purposes of application to male identification, population genetics and population history. With nine markers, every male in a German population sample (n = 70) could be identified by an individual-specific Y microsatellite haplotype. The analysis of 474 unrelated males of nine human populations with seven markers revealed 301 different Y haplotypes. The analysis of molecular variance (AMOVA) approach was used to detect male population characteristics of Y microsatellite haplotypes. With pairwise comparisons of inter-population variance, most of the populations could be distinguished significantly. Sixty individuals from different male populations in Asia and Northern Europe carrying a novel Y-chromosomal T-->C transition show reduced microsatellite variability together with haplotype similarities. Microsatellite data suggest that the mutation occurred recently in Asia, supporting the hypothesis of Asian ancestry of some northern European populations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0173-0835
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1602-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9378129-Asia,
pubmed-meshheading:9378129-Europe,
pubmed-meshheading:9378129-Genetics, Population,
pubmed-meshheading:9378129-Haplotypes,
pubmed-meshheading:9378129-Humans,
pubmed-meshheading:9378129-Male,
pubmed-meshheading:9378129-Minisatellite Repeats,
pubmed-meshheading:9378129-Mutation,
pubmed-meshheading:9378129-Polymerase Chain Reaction,
pubmed-meshheading:9378129-Y Chromosome
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pubmed:year |
1997
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pubmed:articleTitle |
Applications of microsatellite-based Y chromosome haplotyping.
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pubmed:affiliation |
Institut für Gerichtliche Medizin, Humboldt-Universität zu Berlin, Germany. kayser@rz.charite.hu-berlin.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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