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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1997-11-10
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pubmed:abstractText |
Our previous report demonstrated that there was impairment of local cellular immunity with elevated interleukin-10 (IL-10) and undetectable IL-12 in neoplastic pleural effusion. These findings suggest that the local immune reactions favor the T-helper type 2 (Th2) pathway instead of Th1 pathway. The present study was designed to examine whether local cellular immunity could be manipulated by IL-2 and/or IL-12 treatment, and to determine their effect on the helper T-cell pathways and the cytolytic activity of the effusion-associated lymphocytes (EALs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Colloids,
http://linkedlifedata.com/resource/pubmed/chemical/Contrast Media,
http://linkedlifedata.com/resource/pubmed/chemical/Diatrizoate,
http://linkedlifedata.com/resource/pubmed/chemical/Ficoll,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-12,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Percoll,
http://linkedlifedata.com/resource/pubmed/chemical/Povidone,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Silicon Dioxide
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0012-3692
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
960-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9377959-Adenocarcinoma,
pubmed-meshheading:9377959-Cell Separation,
pubmed-meshheading:9377959-Cells, Cultured,
pubmed-meshheading:9377959-Centrifugation,
pubmed-meshheading:9377959-Colloids,
pubmed-meshheading:9377959-Contrast Media,
pubmed-meshheading:9377959-Cytotoxicity, Immunologic,
pubmed-meshheading:9377959-Diatrizoate,
pubmed-meshheading:9377959-Ficoll,
pubmed-meshheading:9377959-Humans,
pubmed-meshheading:9377959-Immune Tolerance,
pubmed-meshheading:9377959-Immunocompetence,
pubmed-meshheading:9377959-Interleukin-10,
pubmed-meshheading:9377959-Interleukin-12,
pubmed-meshheading:9377959-Interleukin-2,
pubmed-meshheading:9377959-Killer Cells, Lymphokine-Activated,
pubmed-meshheading:9377959-Killer Cells, Natural,
pubmed-meshheading:9377959-Lung Neoplasms,
pubmed-meshheading:9377959-Lymphocyte Activation,
pubmed-meshheading:9377959-Lymphocytes,
pubmed-meshheading:9377959-Lymphocytes, Tumor-Infiltrating,
pubmed-meshheading:9377959-Pleural Effusion, Malignant,
pubmed-meshheading:9377959-Povidone,
pubmed-meshheading:9377959-Recombinant Proteins,
pubmed-meshheading:9377959-Silicon Dioxide,
pubmed-meshheading:9377959-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:9377959-Th1 Cells,
pubmed-meshheading:9377959-Th2 Cells
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pubmed:year |
1997
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pubmed:articleTitle |
Cross regulation by IL-10 and IL-2/IL-12 of the helper T cells and the cytolytic activity of lymphocytes from malignant effusions of lung cancer patients.
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pubmed:affiliation |
Chest Department, Veterans General Hospital-Taipei, Taiwan, ROC.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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