|
rdf:type |
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lifeskim:mentions |
umls-concept:C0011923,
umls-concept:C0030567,
umls-concept:C0114838,
umls-concept:C0205307,
umls-concept:C0380193,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C1709793,
umls-concept:C2349001,
umls-concept:C2697811
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pubmed:issue |
11
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pubmed:dateCreated |
1997-12-11
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pubmed:abstractText |
Iodine-123-N-(3-iodopropene-2-yl)-2beta-carbomethoxy-3beta-( 4-chlorophenyl) tropane (123I-IPT) is a new dopamine transporter ligand that selectively binds the dopamine reuptake sites. Transporter concentrations have been known to decrease in Parkinson's disease patients. The purpose of this study was to evaluate the usefulness of IPT as an imaging agent for measuring changes in transporter concentrations in Parkinson's disease.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0161-5505
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1703-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9374337-Adult,
pubmed-meshheading:9374337-Brain,
pubmed-meshheading:9374337-Carrier Proteins,
pubmed-meshheading:9374337-Case-Control Studies,
pubmed-meshheading:9374337-Dopamine,
pubmed-meshheading:9374337-Dopamine Plasma Membrane Transport Proteins,
pubmed-meshheading:9374337-Female,
pubmed-meshheading:9374337-Humans,
pubmed-meshheading:9374337-Iodine Radioisotopes,
pubmed-meshheading:9374337-Male,
pubmed-meshheading:9374337-Membrane Glycoproteins,
pubmed-meshheading:9374337-Membrane Transport Proteins,
pubmed-meshheading:9374337-Middle Aged,
pubmed-meshheading:9374337-Nerve Tissue Proteins,
pubmed-meshheading:9374337-Parkinson Disease,
pubmed-meshheading:9374337-Time Factors,
pubmed-meshheading:9374337-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:9374337-Tropanes
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pubmed:year |
1997
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pubmed:articleTitle |
Imaging and quantitation of dopamine transporters with iodine-123-IPT in normal and Parkinson's disease subjects.
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pubmed:affiliation |
Department of Nuclear Medicine, Asan Medical Center, University of Ulsan, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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