Linked Life Data

9374317

Source:http://linkedlifedata.com/resource/pubmed/id/9374317

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1998-1-27
pubmed:abstractText
The ultrastructural and immunoreactive staining characteristics of cells containing prolactin (lactotropes) and growth hormone (GH; somatotropes) in the anterior pituitaries of gonadally intact pony mares were studied at the electron microscopic level. Lactotropes included two morphological subsets: Type I cells were larger and contained large, dense, polymorphic granules that were scattered throughout the cytoplasm; Type II cells were smaller and contained small, dense, polymorphic granules that were predominantly found in peripheral areas of the cytoplasm. Lactotropes constituted 5 to 16% of the total number of cells in the pituitary. Somatotropes were medium-sized cells containing uniform, large, dense secretory granules. The somatotropes contained the largest secretory granules in the pituitary and represented 11 to 26% of the total number of cells. Type I lactotropes and somatotropes were readily distinguishable without immunocytochemical staining. Double-labeling of pituitary sections allowed for characterization of cells that contained both hormones (mammosomatotropes). These cells were morphologically indistinguishable from Type I lactotropes and constituted 6.5 to 16.5% of the total number of cells. Results from this study demonstrated that there are two cell populations that contain only prolactin (Type I and II lactotropes) and one cell population that contains only GH (somatotropes) in the equine pituitary, and an additional subset of cells that contains GH and prolactin in the same secretory granules.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-8812
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3010-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Immunocytochemical localization of prolactin and growth hormone in the equine pituitary.
pubmed:affiliation
Department of Animal Science, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge 70803, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't