Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1976-8-23
pubmed:abstractText
Quantitative polyacrylamide disk gel electrophoresis of sera from 27 patients with Sjögren's syndrome (SS) and 12 comparable normal subjects revealed that serum amylase activity in patients with SS varies due to changes in the salivary isoenzyme, while pancreatic isoamylase remains normal. The SS group can be divided into those patients with markedly increased salivary isoamylase and those with normal or low salivary isoamylase. At this time we cannot be certain whether this reflects different stages in a progressive disorder, or differences in the underlying pathologic processes. Analysis of amylase isoenzymes in serum previously has been shown to be of value in pancreatic disorders, and we have now demonstrated that changes in the salivary glands may also be relected in serum amylase isoenzymes. Study of patients with other salivary and pancreatic disorders will be needed to define the clinical utility of amylase isoenzyme analysis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1022-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Changes in serum salivary isoamylases in Sjögren's Syndrome.
pubmed:publicationType
Journal Article