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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1998-1-13
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pubmed:abstractText |
The retinal pigment epithelium (RPE) forms the outer blood-retinal barrier by separating the neural retina from fenestrated capillaries in the choroid. The barrier depends upon tight junctions within the apical junctional complexes that bind neighboring cells. During development, permeability decreases as the apical junctional complex gradually matures. To investigate this process, the composition of the apical junctional complex was monitored during RPE development in chicken embryos.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-276X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
249
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
380-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9372172-Animals,
pubmed-meshheading:9372172-Blood-Retinal Barrier,
pubmed-meshheading:9372172-Capillary Permeability,
pubmed-meshheading:9372172-Chick Embryo,
pubmed-meshheading:9372172-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:9372172-Histocytochemistry,
pubmed-meshheading:9372172-Horseradish Peroxidase,
pubmed-meshheading:9372172-Immunoblotting,
pubmed-meshheading:9372172-Membrane Proteins,
pubmed-meshheading:9372172-Microscopy, Electron,
pubmed-meshheading:9372172-Phosphoproteins,
pubmed-meshheading:9372172-Staining and Labeling,
pubmed-meshheading:9372172-Tight Junctions
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pubmed:year |
1997
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pubmed:articleTitle |
Remodeling of junctional complexes during the development of the outer blood-retinal barrier.
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pubmed:affiliation |
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520-8062, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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