Linked Life Data

9372004

Source:http://linkedlifedata.com/resource/pubmed/id/9372004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-1-16
pubmed:abstractText
The application of recent discoveries in the field of molecular oncology to acute myeloid and lymphoblastic leukemia has provided new insights into the pathogenesis and natural history of these diseases. Cytogenetic abnormalities and the detection of mutations or abnormal expression of certain oncogenes or tumor suppressor genes now provide powerful prognostic information to guide choice of therapy and prediction of response. Randomized trials of intensive postremission chemotherapy have now confirmed improved leukemia-free survival with the use of high-dose cytarabine or allogeneic or autologous bone marrow transplantation. Progress in the treatment of acute myeloid leukemia and acute lymphocytic leukemia in the elderly, where the prevalence of these diseases is likely to increase as our population ages, has been more modest. There is still a need for the evaluation of new treatment strategies in previously untreated patients with acute leukemia, despite the progress that has been reported during the past year.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1065-6251
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
247-54
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Acute leukemia in adults.
pubmed:affiliation
Toronto Hospital, Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article, Review