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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1998-1-16
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pubmed:abstractText |
Porcine pulmonary surfactant-associated protein SP-C was incorporated into bilayers of chain-perdeuterated dipalmitoylphosphatidylglycerol (DPPG-d62) and chain-perdeuterated dipalmitoyl-phosphatidylcholine (DPPC-d62) and into bilayers containing 70 mol% dipalmitoyl-phosphatidylcholine (DPPC) and 30 mol% DPPG-d62 or 70 mol% DPPC-d62 and 30 mol% dipalmitoylphosphatidylglycerol (DPPG). The effect of SP-C on the phase behavior, lipid chain order, and dynamics in these bilayers was examined by using deuterium nuclear magnetic resonance. SP-C was found to have a similar effect on the chain order and phase behavior of DPPC-d62 and DPPG-d62 in bilayers with a single lipid component. In gel phase DPPC/DPPG (7:3) bilayers with one or the other lipid component chain-perdeuterated, SP-C was found to affect first spectral moment more strongly for DPPG-d62 than for DPPC-d62. This may indicate that SP-C induced a nonrandom lateral distribution in the mixed lipid bilayer. SP-C was also found to influence motions responsible for deuteron transverse relaxation in both the gel and liquid crystalline phases. The presence of 5 mM Ca2+ in the aqueous phase substantially altered the effect of SP-C on transverse relaxation in the bilayer.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-13641241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1390721,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1497860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1691657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1730226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1868098,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1911771,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-1991023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-2383558,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-2454132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-3240564,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-3382650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-3607053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-4006876,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-5085985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-6337629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-6478029,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-7491974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-7696261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-7993894,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-8162991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9370454-9100011
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,2-Dipalmitoylphosphatidylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/1,2-dipalmitoylphosphatidylglycerol,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Deuterium,
http://linkedlifedata.com/resource/pubmed/chemical/Gels,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Bilayers,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylglycerols,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids,
http://linkedlifedata.com/resource/pubmed/chemical/Proteolipids,
http://linkedlifedata.com/resource/pubmed/chemical/Pulmonary Surfactants
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-3495
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2595-602
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:9370454-1,2-Dipalmitoylphosphatidylcholine,
pubmed-meshheading:9370454-Animals,
pubmed-meshheading:9370454-Calcium,
pubmed-meshheading:9370454-Deuterium,
pubmed-meshheading:9370454-Gels,
pubmed-meshheading:9370454-Lipid Bilayers,
pubmed-meshheading:9370454-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9370454-Phosphatidylglycerols,
pubmed-meshheading:9370454-Phospholipids,
pubmed-meshheading:9370454-Proteolipids,
pubmed-meshheading:9370454-Pulmonary Surfactants,
pubmed-meshheading:9370454-Swine,
pubmed-meshheading:9370454-Temperature
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pubmed:year |
1997
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pubmed:articleTitle |
Effect of calcium on phospholipid interaction with pulmonary surfactant protein C.
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pubmed:affiliation |
Department of Physics and Physical Oceanography, Memorial University of Newfoundland, St. John's, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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