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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
5
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pubmed:dateCreated |
1997-12-8
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pubmed:abstractText |
Recombinant interleukin-2 (rIL-2) therapy for advanced malignancy is usually associated with a vascular leak syndrome (VLS) similar to that seen in severe sepsis. We investigated the possibility that the IL-2-induced VLS may be associated with the presence of circulating activated polymorphonuclear (PMN) leukocytes as occurs in sepsis syndrome.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD18,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-DR Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Macrophage-1 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0039-6060
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
918-26
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9369892-Antigens, CD,
pubmed-meshheading:9369892-Antigens, CD18,
pubmed-meshheading:9369892-Carcinoma, Renal Cell,
pubmed-meshheading:9369892-Flow Cytometry,
pubmed-meshheading:9369892-Granulocytes,
pubmed-meshheading:9369892-HLA-DR Antigens,
pubmed-meshheading:9369892-Humans,
pubmed-meshheading:9369892-Hydrogen Peroxide,
pubmed-meshheading:9369892-Immunophenotyping,
pubmed-meshheading:9369892-Infusions, Intravenous,
pubmed-meshheading:9369892-Interleukin-2,
pubmed-meshheading:9369892-Kidney Neoplasms,
pubmed-meshheading:9369892-Lymphocytes,
pubmed-meshheading:9369892-Macrophage-1 Antigen,
pubmed-meshheading:9369892-Melanoma,
pubmed-meshheading:9369892-Neutrophils,
pubmed-meshheading:9369892-Receptors, Interleukin-2,
pubmed-meshheading:9369892-Recombinant Proteins,
pubmed-meshheading:9369892-Up-Regulation
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pubmed:year |
1997
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pubmed:articleTitle |
Neutrophil activation, vascular leak toxicity, and cytolysis during interleukin-2 infusion in human cancer.
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pubmed:affiliation |
University Department of Surgery, University of Wales College of Medicine, Heathpark, Cardiff, U.K.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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