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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1997-11-25
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pubmed:abstractText |
We recently changed from using fine needle aspiration cytology to using core biopsy exclusively in the assessment of screen detected abnormalities. Two hundred and two biopsies (1% of women screened) were performed. Surgical histological confirmation was obtained in 111 patients (101 malignant and 10 benign). The remaining patients were either returned to standard 3-yearly screening or early repeat screening after 1 year. Analysis of the results was performed in accordance with the standards specified in the National Health Service Breast Screening Programme (NHSBSP) Publication Number 22. Absolute sensitivity was 89.3%, complete sensitivity was 93.2%, specificity (including patients undergoing both surgical excision and follow-up) was 88.7%. The predictive value of a positive (malignant) core biopsy result was 100%. The false negative rate was 3.9%. Twelve (5.9%) biopsies were classified inadequate for diagnosis. Core biopsy is a safe and accurate way of assessing screen detected abnormalities and can be used as a substitute for fine needle aspiration cytology with results that exceed the National Health Service Breast Screening Programme target standards, even in the learning phase.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0009-9260
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
764-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9366536-Biopsy,
pubmed-meshheading:9366536-Biopsy, Needle,
pubmed-meshheading:9366536-Breast Neoplasms,
pubmed-meshheading:9366536-False Negative Reactions,
pubmed-meshheading:9366536-Female,
pubmed-meshheading:9366536-Great Britain,
pubmed-meshheading:9366536-Humans,
pubmed-meshheading:9366536-Mammography,
pubmed-meshheading:9366536-Mass Screening,
pubmed-meshheading:9366536-Predictive Value of Tests,
pubmed-meshheading:9366536-Sensitivity and Specificity,
pubmed-meshheading:9366536-State Medicine,
pubmed-meshheading:9366536-Ultrasonography, Interventional,
pubmed-meshheading:9366536-Ultrasonography, Mammary
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pubmed:year |
1997
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pubmed:articleTitle |
Changing to core biopsy in an NHS breast screening unit.
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pubmed:affiliation |
Department of Radiology, Addenbrooke's Hospital and Cambridge University, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|