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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1998-1-27
|
| pubmed:abstractText |
Growth and development were monitored for up to 42 months in nine neonates to whom ciprofloxacin, a fluoroquinolone, was given in the neonatal period at a dosage of 20 mg/kg/day. Ciprofloxacin was used only as a ¿life-saving' therapy in cases of sepsis produced by bacterial agents resistant to other antibiotics. Two other groups of nine neonates, matched by birth weight and gestational age, were studied as controls: one group with sepsis, which was effectively treated with cefotaxime and a group of healthy neonates. No statistically significant differences in growth and development between the groups were found during follow-up for 42 months. No osteoarticular problems or joint deformities were observed in the ciprofloxacin group. Ciprofloxacin appears to provide a therapeutic option as a ¿life-saving' therapy for newborns with sepsis produced by multiply resistant organisms.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0300-0605
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
302-6
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9364293-Anti-Infective Agents,
pubmed-meshheading:9364293-Body Height,
pubmed-meshheading:9364293-Body Weight,
pubmed-meshheading:9364293-Cefotaxime,
pubmed-meshheading:9364293-Cephalosporins,
pubmed-meshheading:9364293-Child, Preschool,
pubmed-meshheading:9364293-Child Development,
pubmed-meshheading:9364293-Ciprofloxacin,
pubmed-meshheading:9364293-Evaluation Studies as Topic,
pubmed-meshheading:9364293-Female,
pubmed-meshheading:9364293-Follow-Up Studies,
pubmed-meshheading:9364293-Gestational Age,
pubmed-meshheading:9364293-Growth,
pubmed-meshheading:9364293-Humans,
pubmed-meshheading:9364293-Infant,
pubmed-meshheading:9364293-Infant, Newborn,
pubmed-meshheading:9364293-Joints,
pubmed-meshheading:9364293-Male,
pubmed-meshheading:9364293-Osteogenesis,
pubmed-meshheading:9364293-Sepsis,
pubmed-meshheading:9364293-Severity of Illness Index,
pubmed-meshheading:9364293-Skull
|
| pubmed:articleTitle |
The effects of a fluoroquinolone on the growth and development of infants.
|
| pubmed:affiliation |
Department of Paediatric Surgery, Uluda? University Faculty of Medicine, Bursa, Turkey.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
|