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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8 Suppl
|
| pubmed:dateCreated |
1997-11-20
|
| pubmed:abstractText |
In the present article, the steps involved in the process of tumor metastasis are discussed. Several events are required for malignant cells to leave the primary tumor and proliferate at a distant site: vessel formation (angiogenesis), cell attachment, invasion (matrix degradation, cell motility), and cell proliferation. Molecular mechanisms underlying each of these steps are described. Based on blocking these processes, new anti-metastasis therapies are being developed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0008-543X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
80
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1529-37
|
| pubmed:dateRevised |
2005-11-16
|
| pubmed:meshHeading |
pubmed-meshheading:9362419-Bone Neoplasms,
pubmed-meshheading:9362419-Cell Adhesion,
pubmed-meshheading:9362419-Cell Adhesion Molecules,
pubmed-meshheading:9362419-Growth Substances,
pubmed-meshheading:9362419-Humans,
pubmed-meshheading:9362419-Neoplasm Invasiveness,
pubmed-meshheading:9362419-Neoplasm Metastasis,
pubmed-meshheading:9362419-Neovascularization, Pathologic,
pubmed-meshheading:9362419-Tissue Inhibitor of Metalloproteinases
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
General mechanisms of metastasis.
|
| pubmed:affiliation |
Laboratory of Pathology, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethseda, Maryland 20892, USA.
|
| pubmed:publicationType |
Journal Article,
Review
|