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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
10
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pubmed:dateCreated |
1997-12-4
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pubmed:abstractText |
A case of endometrial stromal sarcoma (ESS) showed cystic pulmonary metastases mimicking lymphangiomyomatosis (LAM). A 58-year-old female, who had undergone total hysterectomy for low-grade ESS 16 years previously, had repeated bouts of pneumothorax. Multiple thin-walled cysts in the peripheral lung were revealed by radiological examinations. In an open-lung biopsy specimen, cystic lesions were surrounded by layers of spindle-shaped cells of varying thickness that resembled LAM. However, in addition to subtle histologic differences from LAM, HMB45 (antimelanoma antibody) showed positive in LAM (n = 3), but was negative in ESS (n = 2) and the cystic lesions of this case. Using myogenic markers (desmin and alpha-smooth muscle actin), metastatic ESS could be immunohistochemically differentiated from mesenchymal cystic hamartoma (n = 1). HMB45 immunohistochemistry is useful in the differential diagnosis of cystic pulmonary lesions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1320-5463
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
725-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9361109-Actins,
pubmed-meshheading:9361109-Antigens, Neoplasm,
pubmed-meshheading:9361109-Biological Markers,
pubmed-meshheading:9361109-Biopsy,
pubmed-meshheading:9361109-Desmin,
pubmed-meshheading:9361109-Diagnosis, Differential,
pubmed-meshheading:9361109-Endometrial Neoplasms,
pubmed-meshheading:9361109-Female,
pubmed-meshheading:9361109-Humans,
pubmed-meshheading:9361109-Immunohistochemistry,
pubmed-meshheading:9361109-Lung Neoplasms,
pubmed-meshheading:9361109-Lymphangioleiomyomatosis,
pubmed-meshheading:9361109-Melanoma-Specific Antigens,
pubmed-meshheading:9361109-Middle Aged,
pubmed-meshheading:9361109-Neoplasm Proteins,
pubmed-meshheading:9361109-Neoplasms, Cystic, Mucinous, and Serous,
pubmed-meshheading:9361109-Sarcoma,
pubmed-meshheading:9361109-Tomography, X-Ray Computed
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pubmed:year |
1997
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pubmed:articleTitle |
Cystic pulmonary metastases of endometrial stromal sarcoma of the uterus, mimicking lymphangiomyomatosis: a case report with immunohistochemistry of HMB45.
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pubmed:affiliation |
Department of Diagnostic Pathology, Kanto Teishin Hospital, Tokyo, Japan. tomooitoh@jsn.justnet.or.jp
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pubmed:publicationType |
Journal Article,
Case Reports
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