rdf:type |
|
lifeskim:mentions |
umls-concept:C0005456,
umls-concept:C0040649,
umls-concept:C0178555,
umls-concept:C1148754,
umls-concept:C1328695,
umls-concept:C1415927,
umls-concept:C1514562,
umls-concept:C1707271,
umls-concept:C1709390,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221
|
pubmed:issue |
11
|
pubmed:dateCreated |
1997-12-4
|
pubmed:abstractText |
The crystal structure of human replication and transcription cofactor PC4CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DNA at promoters or origins of replication.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1072-8368
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
900-3
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9360603-Amino Acid Sequence,
pubmed-meshheading:9360603-Binding Sites,
pubmed-meshheading:9360603-Crystallography, X-Ray,
pubmed-meshheading:9360603-DNA, Single-Stranded,
pubmed-meshheading:9360603-Dimerization,
pubmed-meshheading:9360603-Humans,
pubmed-meshheading:9360603-Immediate-Early Proteins,
pubmed-meshheading:9360603-Membrane Proteins,
pubmed-meshheading:9360603-Models, Molecular,
pubmed-meshheading:9360603-Molecular Sequence Data,
pubmed-meshheading:9360603-Repressor Proteins,
pubmed-meshheading:9360603-Trans-Activators
|
pubmed:year |
1997
|
pubmed:articleTitle |
C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site.
|
pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
|