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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1980-4-23
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pubmed:abstractText |
The nutritive value of N-acetyl-L-tryptophan was investigated by loading tests with deuterated L-tryptophan and deuterated N-acetyl-L-tryptophan in three healthy adults, and by a 7 day-long feeding experiment with deuterated N-acetyl-L-tryptophan in one healthy adult. After loading with deuterated N-acetyl-L-tryptophan, serum levels of deuterated tryptophan and kynurenine were only about 10%, and the amounts of deuterated 5-hydroxyindole-3-acetic acid excreted in 24 h approximately 30% of those found after deuterated tryptophan loading. During the feeding experiment with deuterated N-acetyl-L-tryptophan, the serum level of deuterated tryptophan remained below 20% of total serum tryptophan, and serum protein fell below the normal range. It is concluded that the nutritive value of N-acetyl-L-tryptophan is inferior to that of L-tryptophan. Contradictory findings of earlier studies are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Deuterium,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyindoleacetic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Kynurenine,
http://linkedlifedata.com/resource/pubmed/chemical/Tryptophan
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pubmed:status |
MEDLINE
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pubmed:issn |
0018-022X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
34
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
497-508
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:93590-Blood Proteins,
pubmed-meshheading:93590-Deuterium,
pubmed-meshheading:93590-Female,
pubmed-meshheading:93590-Humans,
pubmed-meshheading:93590-Hydroxyindoleacetic Acid,
pubmed-meshheading:93590-Kynurenine,
pubmed-meshheading:93590-Male,
pubmed-meshheading:93590-Nutritive Value,
pubmed-meshheading:93590-Tryptophan
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pubmed:year |
1979
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pubmed:articleTitle |
Nutritive value of N-acetyl-L-tryptophan in man.
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pubmed:publicationType |
Journal Article
|