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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1997-12-16
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pubmed:abstractText |
Triple quantum (TQ)-filtered 23Na NMR spectroscopy and the shift reagent, TmDOTP5-, have been used to evaluate the contributions of intra- (Na+i) and extracellular (Na+e) sodium to the TQ-filtered signal in the rat liver, in situ. Na+e contributed significantly to the total TQ-filtered signal in live animals, and the intensity of this signal did not change postmortem. The TQ-filtered Na+i signal increased by approximately 380% over a period of 1 h postmortem, whereas the single quantum (SQ) Na+i increased by 90%. The constancy of the TQ-filtered Na+i signal indicates that changes in total TQ-filtered 23Na signal intensity in liver (without a shift reagent) may accurately reflect changes in TQ-filtered Na+i signal intensity. The large percent increase in the TQ-filtered Na+i signal as compared to the SQ signal suggests that the fraction of Na+i interacting with macromolecules increases after death.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Organometallic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Organophosphorus Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium,
http://linkedlifedata.com/resource/pubmed/chemical/Thulium,
http://linkedlifedata.com/resource/pubmed/chemical/thulium(III)...
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0740-3194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
821-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9358457-Animals,
pubmed-meshheading:9358457-Liver,
pubmed-meshheading:9358457-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9358457-Male,
pubmed-meshheading:9358457-Organometallic Compounds,
pubmed-meshheading:9358457-Organophosphorus Compounds,
pubmed-meshheading:9358457-Rats,
pubmed-meshheading:9358457-Rats, Sprague-Dawley,
pubmed-meshheading:9358457-Sodium,
pubmed-meshheading:9358457-Thulium
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pubmed:year |
1997
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pubmed:articleTitle |
Evaluation of triple quantum-filtered 23Na NMR spectroscopy in the in situ rat liver.
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pubmed:affiliation |
Mary Nell and Ralph B. Rogers Magnetic Resonance Center, Department of Radiology, University of Texas Southwestern Medical Center, Dallas 75235-9085, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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