| pubmed-article:9351801 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0027754 | lld:lifeskim |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0027752 | lld:lifeskim |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0242210 | lld:lifeskim |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
| pubmed-article:9351801 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:9351801 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:9351801 | pubmed:dateCreated | 1998-1-6 | lld:pubmed |
| pubmed-article:9351801 | pubmed:abstractText | Nerve growth factor (NGF) is a neurotrophic factor that promotes the differentiation and survival of certain populations of neurons in the central and peripheral nervous systems. 7S NGF is an alpha 2 beta 2 gamma 2 complex in which the beta-NGF dimer (the active neurotrophin) is associated with two alpha-NGF and two gamma-NGF subunits, which belong to the glandular kallikrein family of serine proteinases. The gamma-NGF subunit is an active serine proteinase capable of processing the precursor form of beta-NGF, whereas alpha-NGF is an inactive serine proteinase. The structure of 7S NGF could be used as a starting point to design inhibitors that prevent NGF binding to its receptors, as a potential treatment of neurodegenerative diseases. | lld:pubmed |
| pubmed-article:9351801 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9351801 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9351801 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9351801 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9351801 | pubmed:issn | 0969-2126 | lld:pubmed |
| pubmed-article:9351801 | pubmed:author | pubmed-author:BlundellT LTL | lld:pubmed |
| pubmed-article:9351801 | pubmed:author | pubmed-author:BanTT | lld:pubmed |
| pubmed-article:9351801 | pubmed:author | pubmed-author:Murray-RustJJ | lld:pubmed |
| pubmed-article:9351801 | pubmed:author | pubmed-author:McDonaldN QNQ | lld:pubmed |
| pubmed-article:9351801 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9351801 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:9351801 | pubmed:volume | 5 | lld:pubmed |
| pubmed-article:9351801 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9351801 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9351801 | pubmed:pagination | 1275-85 | lld:pubmed |
| pubmed-article:9351801 | pubmed:dateRevised | 2010-10-5 | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:meshHeading | pubmed-meshheading:9351801-... | lld:pubmed |
| pubmed-article:9351801 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9351801 | pubmed:articleTitle | Structure of mouse 7S NGF: a complex of nerve growth factor with four binding proteins. | lld:pubmed |
| pubmed-article:9351801 | pubmed:affiliation | Department of Crystallography, Birkbeck College, London, UK. b.bax@cryst.bbk.ac.uk | lld:pubmed |
| pubmed-article:9351801 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:4803 | entrezgene:pubmed | pubmed-article:9351801 | lld:entrezgene |
| entrez-gene:18048 | entrezgene:pubmed | pubmed-article:9351801 | lld:entrezgene |
| entrez-gene:18049 | entrezgene:pubmed | pubmed-article:9351801 | lld:entrezgene |
| entrez-gene:18050 | entrezgene:pubmed | pubmed-article:9351801 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:9351801 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9351801 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9351801 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9351801 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9351801 | lld:pubmed |
