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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1997-12-15
|
| pubmed:abstractText |
The photons of sunlight precipitate a series of genetic events in skin leading to cancer. These events involve somatic mutations as well as inherited alleles. Competition between cell populations ensues, as a single mutated cell expands into a clone. Thus cancer involves both a single-cell problem and a many-cell problem; in skin cancer, sunlight appears to drive both.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0168-9525
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
410-4
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9351343-Apoptosis,
pubmed-meshheading:9351343-Carcinoma, Basal Cell,
pubmed-meshheading:9351343-Carcinoma, Squamous Cell,
pubmed-meshheading:9351343-Genes, p53,
pubmed-meshheading:9351343-Humans,
pubmed-meshheading:9351343-Mutation,
pubmed-meshheading:9351343-Skin Neoplasms,
pubmed-meshheading:9351343-Sunlight,
pubmed-meshheading:9351343-Ultraviolet Rays
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Sunlight and the onset of skin cancer.
|
| pubmed:affiliation |
Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT 06520-8040, USA. douglas.brash@yale.edu
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|