Linked Life Data

9351285

Source:http://linkedlifedata.com/resource/pubmed/id/9351285

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1998-1-7
pubmed:abstractText
Delivery of drugs to the nervous system remains a challenge despite advances in our understanding of the mechanisms involved in the development of neurodegenerative disorders and the actions of neuroactive agents. Drug accessibility to the central nervous system is limited by the blood-brain barrier; although the peripheral nervous system is more accessible than the central nervous system, problems are still encountered, mainly owing to the poor stability and considerable side effects of many neuroactive compounds when administered systemically. Microencapsulation of neuroactive compounds and living cells producing such substances can overcome some of these shortcomings for delivery to the nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
B
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0167-7799
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
410-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Drug delivery to the nervous system.
pubmed:affiliation
Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada. dmaysing@pharma.mcgill.ca
pubmed:publicationType
Journal Article, Review