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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1997-11-28
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pubmed:abstractText |
Klinefelter's syndrome is a genetic disorder of male sexual differentiation characterized by an XXY karyotype. Although considered a benign condition, it is associated with several types of malignancies, including mediastinal germ-cell neoplasm. In addition, Klinefelter's syndrome has been rarely associated with testicular microlithiasis. Whereas patients with Klinefelter's syndrome have an increased incidence of extragonadal germ-cell neoplasms, patients with testicular microlithiasis have a predisposition to testicular germ-cell neoplasms. To our knowledge, an extragonadal germ-cell neoplasm has not been previously described in association with testicular microlithiasis. We present a patient with 2 unusual conditions, both of which are independently associated with Klinefelter's syndrome: mediastinal germ-cell neoplasm and testicular microlithiasis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0091-2751
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
508-10
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9350572-Adolescent,
pubmed-meshheading:9350572-Calculi,
pubmed-meshheading:9350572-Humans,
pubmed-meshheading:9350572-Klinefelter Syndrome,
pubmed-meshheading:9350572-Male,
pubmed-meshheading:9350572-Mediastinal Neoplasms,
pubmed-meshheading:9350572-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:9350572-Neoplasms, Multiple Primary,
pubmed-meshheading:9350572-Testicular Diseases,
pubmed-meshheading:9350572-Tomography, X-Ray Computed
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pubmed:articleTitle |
Klinefelter's syndrome associated with testicular microlithiasis and mediastinal germ-cell neoplasm.
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pubmed:affiliation |
Department of Radiology, University of Illinois Hospital, Chicago 60612, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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