Linked Life Data

9347478

Source:http://linkedlifedata.com/resource/pubmed/id/9347478

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1998-1-30
pubmed:abstractText
Both clinical reports and systematic neuropsychological studies have shown that patients with damage to selected brain sites develop defects in the retrieval of conceptual knowledge for various concrete entities, leading to the hypothesis that the retrieval of knowledge for entities from different conceptual categories depends on partially segregated large-scale neural systems. To test this hypothesis, 116 subjects with focal, unilateral lesions to various sectors of the telencephalon, and 55 matched controls, were studied with a procedure which required the visual recognition of entities from three categories--unique persons, non-unique animals and non-unique tools. Defective recognition of persons was associated with maximal lesion overlap in right temporal polar region; defective recognition of animals was associated with maximal lesion overlap in right mesial occipital/ventral temporal region and also in left mesial occipital region; and defective recognition of tools was associated with maximal lesion overlap in the occipital-temporal-parietal junction of the left hemisphere. The findings support the hypothesis that the normal retrieval of knowledge for concrete entities from different conceptual domains depends on partially segregated neural systems. These sites may operate as catalysts for the retrieval of the multidimensional aspects of knowledge which are necessary and sufficient for the mental representation of a concept of a given entity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0028-3932
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1319-27
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
A neural basis for the retrieval of conceptual knowledge.
pubmed:affiliation
Department of Neurology, University of Iowa College of Medicine, Iowa City, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.