Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-12-19
pubmed:abstractText
Smoking is a well-known risk factor for cardiovascular disease, although understanding of the pathophysiological mechanism is incomplete. The effect of heavy smoking, for more than 20 years and of 20 cigarettes per day, on aortic stiffness was studied in women (n = 23, age range 43-61 years) and men (n = 21, age range 43-61 years) who smoked but were otherwise healthy and compared with a healthy reference population that did not smoke. Aortic stiffness (beta) was calculated from the diameter and the pulsatile diameter change determined non-invasively using an ultrasonic echo-tracking system and blood pressure obtained by the auscultatory method. The results showed that aortic diameter did not differ in smoking males (P = 0.974) or in smoking females (P = 0.361). Aortic stiffness was increased in the female (P = 0.041) but not male smokers (P = 0.222). Systolic, mean and diastolic blood pressure in the men and women who smoked did not differ from those in the healthy reference population. In conclusion, this investigation shows increased aortic stiffness in female but not in male smokers. It indicates that the aorta of women might be more vulnerable to smoking with regard to stiffening and degeneration than the aorta of men.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0144-5979
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-47
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Does long-term smoking affect aortic stiffness more in women than in men?
pubmed:affiliation
Department of Vascular and Renal Diseases, Lund University, Malmö University Hospital, Sweden.
pubmed:publicationType
Journal Article, Comparative Study