Linked Life Data

934716

Source:http://linkedlifedata.com/resource/pubmed/id/934716

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-9-1
pubmed:abstractText
In an effort to examine whether normal blood gas tensions were essential for conditioning, paralyzed rats received a classical aversive heart rate (HR) conditioning session while respirated at different peak expired CO2 values. After the session, arterial blood was drawn for analysis. That peak expired CO2 was effective in manipulating PCO2 was indicated by a significant correlation (r=0.594, df=17, P less than 0.05). In addition, only rats with blood gas values similar to those of anesthetized controls displayed a discriminated HR CR. These animals also had lower baseline HRs and greater HR variability. Further, 7 of the 9 rats with normal blood gas values were respirated at peak expired CO2 values from 5.0-5.1 per cent, and no animal ventilated within this range displayed abnormal values. These findings suggest that previous difficulties in obtaining calssical and operant conditioning in paralyzed animals may, in part, be attributable to inadequate ventilation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0093-2213
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
76-85
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Classical aversive conditioning of heart rate in curarized rats at different blood gas levels.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.