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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1997-12-23
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pubmed:abstractText |
Sialic acids comprise a large family of N- and O-substituted neuraminic acid derivatives as components of glycoconjugates. N-Glycolylneuraminic acid is formed from N-acetylneuraminic acid by the action of the CMP-N-acetylneuraminic acid hydroxylase studied in various animals. O-Methylated sialic acids originate from the action of S-adenosylmethionine-8-O-methyltransferase studied in starfish. Sialic acids are O-acetylated at diverse positions by the action of acetyl-CoA-4-O- and -7-O-acetyltransferases found in various animals and, leading to the O-acetylation of sialic acid glycerol side chain, also in man. Some properties of these enzymes are described and biological implications discussed.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-1208
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pubmed:author |
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|
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
131-41
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
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pubmed:articleTitle |
Functional and biosynthetic aspects of sialic acid diversity.
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pubmed:affiliation |
Biochemisches Institut, Christian-Albrechts-Universität zu Kiel, Germany. schauer@biochem.uni-kiel.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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