Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-11-20
pubmed:abstractText
Accurate estimation of quality of life is critical to cost-effectiveness analysis. Nevertheless, development of sampling algorithms to maximize the accuracy and efficiency of estimated quality of life has received little consideration to date. This paper presents a method to optimize sampling strategies for estimating quality-adjusted life years. In particular, the authors address the questions of when to sample and how many observations to sample at each sampling time, assuming realistically that the sample variance of quality of life is not constant over time. The method is particularly useful for the design problems researchers face when time or research budget constraints limit the number of individuals that can be surveyed to estimate quality of life. The article focuses on cross-sectional sampling. The method proposed requires some knowledge of survival in the population of interest, the approximate variances in utilities at various points along the curve, and the general shape of the quality-adjusted survival curve. Such data are frequently available from disease registries, the literature, or previous studies.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0272-989X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
431-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Optimizing sampling strategies for estimating quality-adjusted life years.
pubmed:affiliation
Department of Medicine, University of Washington Medical Center, Seattle, USA. sramsey@u.washington.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.