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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
1997-12-1
|
| pubmed:abstractText |
A community-based longitudinal study conducted in rural Bangladesh investigated the association between nutritional status, cell-mediated immune status and acute upper respiratory infections (URI). A total of 696 children aged 0-59 months was followed prospectively for 1 y yielding 183,865 child-days' observation. Trained field workers visited each child every 4th d and collected morbidity data on symptoms suggesting URI (cough, fever, nasal discharge) for the preceding 3 d by recall. On the day of visit they examined each child reporting cough and/or fever to record the temperature, presence of nasal discharge, rate of respiration and presence of chest indrawing. Anthropometry for all children was conducted monthly. Cell-mediated immune competence was assessed by a multiple antigen skin test at baseline and thereafter every 3 months. The incidence of URI was 5.3 episodes per child-year observed. Approximately three-quarters of the study children were below -2 Z-score weight for age and height for age, and a quarter below -2 Z-score weight for height. During different test periods 9-21% of the study children did not respond to any of the test antigens. In a regression model children < -2 Z-score for weight for height had 16% [odds ratio (OR) 1.16, 95% confidence interval (CI) 1.03-1.31, p = 0.01] higher risk of developing URI. Anergic children had 20% higher risk (OR 1.20, CI 1.05-1.38, p = 0.009) of URI than immunocompetent children. The study demonstrated that wasting and depressed cell-mediated immunity (CMI), but not stunting, were associated with the incidence of URI among rural Bangladeshi children.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0803-5253
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
86
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
923-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9343268-Anthropometry,
pubmed-meshheading:9343268-Bangladesh,
pubmed-meshheading:9343268-Child, Preschool,
pubmed-meshheading:9343268-Developing Countries,
pubmed-meshheading:9343268-Female,
pubmed-meshheading:9343268-Follow-Up Studies,
pubmed-meshheading:9343268-Humans,
pubmed-meshheading:9343268-Immune Tolerance,
pubmed-meshheading:9343268-Immunity, Cellular,
pubmed-meshheading:9343268-Immunologic Deficiency Syndromes,
pubmed-meshheading:9343268-Infant,
pubmed-meshheading:9343268-Longitudinal Studies,
pubmed-meshheading:9343268-Male,
pubmed-meshheading:9343268-Nutrition Surveys,
pubmed-meshheading:9343268-Prospective Studies,
pubmed-meshheading:9343268-Protein-Energy Malnutrition,
pubmed-meshheading:9343268-Respiratory Tract Infections,
pubmed-meshheading:9343268-Risk,
pubmed-meshheading:9343268-Rural Population
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Malnutrition, cell-mediated immune deficiency and acute upper respiratory infections in rural Bangladeshi children.
|
| pubmed:affiliation |
International Centre for Diarrhoeal Disease Research, Bangladesh.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|