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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10 Pt 1
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pubmed:dateCreated |
1997-11-19
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pubmed:abstractText |
Vestibular and optokinetic function was quantitatively studied in the normal guinea pig through investigation of the vestibulo-ocular reflex (VOR), optokinetic nystagmus (OKN), and the visual vestibulo-ocular reflex (VVOR) by means of sinusoidal stimulation with a computer-controlled rate table (VOR and VVOR) or an optokinetic drum. The VOR exhibited high-pass filter characteristics with steady state gain achieved at 0.125 Hz. The maximum gain was 0.55 at a velocity of 60 degrees/s. The VOR was modeled by a transfer function with best fits obtained with an adaptation time constant of 12.5 seconds. The OKN showed low-pass filter characteristics with a decrease in gain for increase in stimulus amplitude. The maximum gain measured was 0.64. A fractional pole model provided a fit of these data. The VVOR exhibited a mean gain of between 0.6 and 0.7 across the stimulus bandwidth and peak velocities. A model based on a linear combination of the actual OKN and VOR gains provided an estimate of the VVOR gain.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-4894
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
838-47
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9342980-Animals,
pubmed-meshheading:9342980-Disease Models, Animal,
pubmed-meshheading:9342980-Endolymphatic Hydrops,
pubmed-meshheading:9342980-Guinea Pigs,
pubmed-meshheading:9342980-Linear Models,
pubmed-meshheading:9342980-Nystagmus, Optokinetic,
pubmed-meshheading:9342980-Physical Stimulation,
pubmed-meshheading:9342980-Reflex, Vestibulo-Ocular,
pubmed-meshheading:9342980-Reproducibility of Results,
pubmed-meshheading:9342980-Rotation,
pubmed-meshheading:9342980-Time Factors
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pubmed:year |
1997
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pubmed:articleTitle |
Vestibular and optokinetic function in the normal guinea pig.
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pubmed:affiliation |
Division of Head and Neck Surgery, University of California-Los Angeles School of Medicine 90095-1624, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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