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rdf:type |
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lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0043076,
umls-concept:C0047678,
umls-concept:C0162801,
umls-concept:C0220781,
umls-concept:C0805701,
umls-concept:C1138842,
umls-concept:C1514873,
umls-concept:C1522642,
umls-concept:C1546857,
umls-concept:C1556066,
umls-concept:C1619636,
umls-concept:C1705535
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pubmed:issue |
2
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pubmed:dateCreated |
1997-12-2
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pubmed:databankReference |
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pubmed:abstractText |
The gl8 locus of maize (Zea mays L.) was previously defined by a mutation that reduces the amount and alters the composition of seedling cuticular waxes. Sixty independently derived gl8 mutant alleles were isolated from stocks that carried the Mutator transposon system. A DNA fragment that contains a Mu8 transposon and that co-segregates with one of these alleles, gl8-Mu3142, was identified and cloned. DNA flanking the Mu8 transposon was shown via allelic cross-referencing experiments to represent the gl8 locus. The gl8 probe revealed a 1.4-kb transcript present in wild-type seedling leaves and, in lesser amounts, in other organs and at other developmental stages. The amino acid sequence deduced from an apparently full-length gl8 cDNA exhibits highly significant sequence similarity to a group of enzymes from plants, eubacteria, and mammals that catalyzes the reduction of ketones. This finding suggests that the GL8 protein probably functions as a reductase during fatty acid elongation in the cuticular wax biosynthetic pathway.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-1333722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-1556094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-16453647,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-2025296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-2231712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-4004258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-4015095,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-4602868,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-6096873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-6312838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-6323258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-6712254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-7734965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-8075637,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-8594577,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-8776898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-8811860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-8820603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9342868-9112770
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0032-0889
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
501-10
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading |
pubmed-meshheading:9342868-Alcohol Oxidoreductases,
pubmed-meshheading:9342868-Amino Acid Sequence,
pubmed-meshheading:9342868-Arabidopsis,
pubmed-meshheading:9342868-Crosses, Genetic,
pubmed-meshheading:9342868-DNA Transposable Elements,
pubmed-meshheading:9342868-Gene Library,
pubmed-meshheading:9342868-Genes, Plant,
pubmed-meshheading:9342868-Genetic Markers,
pubmed-meshheading:9342868-Hordeum,
pubmed-meshheading:9342868-Molecular Sequence Data,
pubmed-meshheading:9342868-Onions,
pubmed-meshheading:9342868-Plant Proteins,
pubmed-meshheading:9342868-Protein Conformation,
pubmed-meshheading:9342868-Sequence Analysis, DNA,
pubmed-meshheading:9342868-Sequence Homology, Amino Acid,
pubmed-meshheading:9342868-Waxes,
pubmed-meshheading:9342868-Zea mays
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pubmed:year |
1997
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pubmed:articleTitle |
Sequence analysis of the cloned glossy8 gene of maize suggests that it may code for a beta-ketoacyl reductase required for the biosynthesis of cuticular waxes.
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pubmed:affiliation |
Department of Zoology, Iowa State University, Ames 50011, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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