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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1997-10-30
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pubmed:abstractText |
Lonidamine (LND) is an energolytic derivative of indazol-carboxylic acid that has been shown to enhance cisplatin (CDDP) activity in both sensitive (A2780) and resistant (A2780/Cp8) ovarian cancer cell lines. The aim of this study was to confirm the potentiating or reverting activity of LND on CDDP activity obtained in experimental models in a phase II study of advanced ovarian cancer patients previously treated with platinum-based regimens.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0732-183X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3208-13
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:9336357-Adult,
pubmed-meshheading:9336357-Aged,
pubmed-meshheading:9336357-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9336357-Carboplatin,
pubmed-meshheading:9336357-Carcinoma,
pubmed-meshheading:9336357-Cisplatin,
pubmed-meshheading:9336357-Drug Synergism,
pubmed-meshheading:9336357-Female,
pubmed-meshheading:9336357-Humans,
pubmed-meshheading:9336357-Indazoles,
pubmed-meshheading:9336357-Middle Aged,
pubmed-meshheading:9336357-Ovarian Neoplasms
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pubmed:year |
1997
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pubmed:articleTitle |
Revertant and potentiating activity of lonidamine in patients with ovarian cancer previously treated with platinum.
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pubmed:affiliation |
Medical Oncology Division, Oncology Institute, Bari, Italy. vlor@mail5.clio.it
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase II
|