Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-11-6
pubmed:abstractText
In vitro collagen binding of 216 Staphylococcus aureus isolates from patients with various diagnoses was studied. Polymerase chain reaction was used to examine these isolates regarding the existence of the corresponding cna gene. Distribution of capsular polysaccharide (CP) types was examined. Fifty-six (57%) of 99 S. aureus isolates from patients with endocarditis or bacteremic bone or joint infection were cna-positive compared with 65 (56%) of 117 isolates from bacteremic patients without signs of bone or joint infection (P = .99). There was a good correlation between in vitro collagen binding and presence of the cna gene. These data suggest that collagen binding is not a prerequisite for the development of endocarditis, osteomyelitis, or septic arthritis. There was no significant difference in the distribution of CP types among various patient groups, although there was a strong association between CP type 8 and the existence of the cna gene.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:volume
176
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1096-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9333176-Antibodies, Bacterial, pubmed-meshheading:9333176-Antigens, Bacterial, pubmed-meshheading:9333176-Bacteremia, pubmed-meshheading:9333176-Bone Diseases, Infectious, pubmed-meshheading:9333176-Carrier Proteins, pubmed-meshheading:9333176-Carrier State, pubmed-meshheading:9333176-Collagen, pubmed-meshheading:9333176-Endocarditis, Bacterial, pubmed-meshheading:9333176-Gene Expression, pubmed-meshheading:9333176-Genes, Bacterial, pubmed-meshheading:9333176-Humans, pubmed-meshheading:9333176-Joint Diseases, pubmed-meshheading:9333176-Nose, pubmed-meshheading:9333176-Polymerase Chain Reaction, pubmed-meshheading:9333176-Polysaccharides, Bacterial, pubmed-meshheading:9333176-Staphylococcal Infections, pubmed-meshheading:9333176-Staphylococcus aureus, pubmed-meshheading:9333176-Wound Infection
pubmed:year
1997
pubmed:articleTitle
Expression of collagen-binding protein and types 5 and 8 capsular polysaccharide in clinical isolates of Staphylococcus aureus.
pubmed:affiliation
Department of Infectious Diseases, University Hospital of Lund, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't