Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-11-20
pubmed:abstractText
This review highlights three topics in which major contributions to lymphoma biology have recently been achieved. First, the use of single-cell polymerase chain reaction analysis has allowed for a better understanding of the origin of several entities, eg, Hodgkin's, Burkitt's, and marginal zone B-cell lymphomas. Second, the studies of mechanisms regulating apoptosis and survival of the neoplastic clones have opened a whole area of research with promising expectations for new therapeutical approaches. Finally, the recent cloning of genes involved in several chromosomal translocations is likely to shed more light on the molecular mechanisms responsible for the neoplastic transformation. The survey presents the main results obtained in these three areas and critically discusses them in the light of the current debate.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1040-8746
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-12
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Recent advances in lymphoma biology.
pubmed:affiliation
Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't