Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1997-11-20
|
| pubmed:abstractText |
IL-10 is a cytokine with suppressive effects on (auto) antigen presentation and T-cell-mediated immune reactions, but is also capable of stimulating polyclonal IgG synthesis. Recent evidence suggests its involvement in multiple sclerosis (MS) and systemic lupus erythematosus (SLE). We assessed PBMNC IL-10 release in MS and SLE patients before and after in vivo prednisone or methylprednisolone treatment. The SLE patients showed a high level of IL-10 release by unstimulated PBMNCs, whereas the PHA-stimulated PBMNCs from MS patients produced large amounts of the cytokine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0392-0461
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
191-4
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9323512-Adult,
pubmed-meshheading:9323512-Aged,
pubmed-meshheading:9323512-Case-Control Studies,
pubmed-meshheading:9323512-Female,
pubmed-meshheading:9323512-Humans,
pubmed-meshheading:9323512-Interleukin-10,
pubmed-meshheading:9323512-Leukocytes, Mononuclear,
pubmed-meshheading:9323512-Lupus Erythematosus, Systemic,
pubmed-meshheading:9323512-Male,
pubmed-meshheading:9323512-Methylprednisolone,
pubmed-meshheading:9323512-Middle Aged,
pubmed-meshheading:9323512-Multiple Sclerosis,
pubmed-meshheading:9323512-Prednisone
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
IL-10 production in multiple sclerosis patients, SLE patients and healthy controls: preliminary findings.
|
| pubmed:affiliation |
Istituto Nazionale Neurologico C. Besta, Milano, Italy.
|
| pubmed:publicationType |
Journal Article
|