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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1997-11-13
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pubmed:abstractText |
Intra-institutional spread of tuberculosis (Tb) has re-emerged as a substantial public and occupational health threat. To characterize the person-hours and lifetime risks of Tb-related morbidity and mortality, we performed a risk assessment for health care workers (HCWs) developing Tb-related morbidity and mortality at varying levels of exposure, engineering controls, and respiratory protection. Under average conditions of exposure, one Tb skin-test conversion is estimated to occur for every 2650 person-hours of work by unprotected workers. With higher exposures, a skin-test conversion for an unprotected worker may occur in as few as 3 person-hours. Use of respiratory protection is estimated to reduce risks by the following proportions: surgical mask, 2.4-fold; disposable dust, fume, mist, or disposable high-efficiency particulate air filtering (HEPA) mask, 17.5-fold; elastomeric HEPA cartridge respirator, 45.5-fold; or powered air-purifying respirator (PAPR), 238-fold. Assuming a lifetime exposure of 250 hours, the risk of a skin-test conversion is estimated to be 9%. We conclude that HCWs are at substantial risk for Tb-related morbidity and mortality, and that administrative controls, engineering controls, and respirators offer substantial benefits in risk reduction.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
1076-2752
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
849-54
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9322168-Humans,
pubmed-meshheading:9322168-Infection Control,
pubmed-meshheading:9322168-Infectious Disease Transmission, Patient-to-Professional,
pubmed-meshheading:9322168-Masks,
pubmed-meshheading:9322168-Models, Theoretical,
pubmed-meshheading:9322168-Poisson Distribution,
pubmed-meshheading:9322168-Respiratory Protective Devices,
pubmed-meshheading:9322168-Risk Assessment,
pubmed-meshheading:9322168-Tuberculin Test,
pubmed-meshheading:9322168-Tuberculosis,
pubmed-meshheading:9322168-Ultraviolet Rays,
pubmed-meshheading:9322168-Ventilation
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pubmed:year |
1997
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pubmed:articleTitle |
Tuberculosis in health care settings and the estimated benefits of engineering controls and respiratory protection.
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pubmed:affiliation |
Department of Medicine, University of Washington, Seattle 98104-2499, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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