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rdf:type |
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lifeskim:mentions |
umls-concept:C0001480,
umls-concept:C0018549,
umls-concept:C0032824,
umls-concept:C0243192,
umls-concept:C0332324,
umls-concept:C0599946,
umls-concept:C0871261,
umls-concept:C0917866,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2709248,
umls-concept:C2911692
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pubmed:issue |
3
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pubmed:dateCreated |
1997-10-16
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pubmed:abstractText |
Lemakalim, an adenosine triphosphate (ATP)-sensitive potassium (K+(ATP)) channel agonist, causes profound pulmonary vasodilation in conscious dogs, which is attenuated during halothane anesthesia. The goal of the present study was to investigate the mechanism responsible for this attenuating effect of halothane.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Inhalation,
http://linkedlifedata.com/resource/pubmed/chemical/Benzopyrans,
http://linkedlifedata.com/resource/pubmed/chemical/Cromakalim,
http://linkedlifedata.com/resource/pubmed/chemical/Glyburide,
http://linkedlifedata.com/resource/pubmed/chemical/Halothane,
http://linkedlifedata.com/resource/pubmed/chemical/Indomethacin,
http://linkedlifedata.com/resource/pubmed/chemical/NG-Nitroarginine Methyl Ester,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-3022
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
625-34
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9316969-Adenosine Triphosphate,
pubmed-meshheading:9316969-Anesthetics, Inhalation,
pubmed-meshheading:9316969-Animals,
pubmed-meshheading:9316969-Benzopyrans,
pubmed-meshheading:9316969-Cromakalim,
pubmed-meshheading:9316969-Dogs,
pubmed-meshheading:9316969-Endothelium, Vascular,
pubmed-meshheading:9316969-Glyburide,
pubmed-meshheading:9316969-Halothane,
pubmed-meshheading:9316969-Humans,
pubmed-meshheading:9316969-Indomethacin,
pubmed-meshheading:9316969-Muscle, Smooth, Vascular,
pubmed-meshheading:9316969-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:9316969-Potassium Channels,
pubmed-meshheading:9316969-Pulmonary Artery,
pubmed-meshheading:9316969-Pyrroles,
pubmed-meshheading:9316969-Vasodilation,
pubmed-meshheading:9316969-Vasodilator Agents
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pubmed:year |
1997
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pubmed:articleTitle |
Halothane attenuates endothelium-dependent pulmonary vasorelaxant response to lemakalim, an adenosine triphosphate (ATP)-sensitive potassium channel agonist.
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pubmed:affiliation |
Division of Anesthesiology and Critical Care Medicine, The Cleveland Clinic Foundation, Ohio 44195, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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