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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1997-11-13
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pubmed:abstractText |
The effects of the serotonin agonist, quipazine, on the induction of c-fos in the suprachiasmatic nucleus of the rat was examined at different times of the 24 h cycle. Quipazine administered at night induced Fos production in a dose dependent manner (1, 3, 10, 30 mumol/kg) in the ventrolateral portion of the suprachiasmatic nucleus at ZT18. Administration of the highest dose at other times resulted in c-fos induction at ZT15 but not at other times of the day or subjective day examined (CT6 and ZT12). When compared to the effects of light pulses (2 lux/1 min), quipazine only caused c-fos induction at times when light caused induction. Our results support a role of serotonergic pathways in the transmission or modulation of photic information from the retina to the suprachiasmatic nucleus of the rat.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
765
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
337-42
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9313909-Animals,
pubmed-meshheading:9313909-Light,
pubmed-meshheading:9313909-Male,
pubmed-meshheading:9313909-Proto-Oncogene Proteins c-fos,
pubmed-meshheading:9313909-Quipazine,
pubmed-meshheading:9313909-Rats,
pubmed-meshheading:9313909-Rats, Wistar,
pubmed-meshheading:9313909-Serotonin Receptor Agonists,
pubmed-meshheading:9313909-Suprachiasmatic Nucleus
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pubmed:year |
1997
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pubmed:articleTitle |
Quipazine and light have similar effects on c-fos induction in the rat suprachiasmatic nucleus.
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pubmed:affiliation |
Department of Obstetrics and Gynaecology, University of Adelaide, Medical School, S.A., Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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