Linked Life Data

9313298

Source:http://linkedlifedata.com/resource/pubmed/id/9313298

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-1-13
pubmed:abstractText
Blastomycosis is a rare but important fungal infection that is diagnosed primarily in the south-central and midwestern United States. Although some patients have subclinical infection and are not treated, the majority of patients with a clinical diagnosis of blastomycosis are treated with antifungal agents. Amphotericin B is curative but, because of toxicity, oral agents have been examined as therapy. Ketoconazole was shown to be effective for less than overwhelming blastomycosis, but adverse effects were relatively common. Itraconazole is a triazole agent that is more effective than ketoconazole, because it is often effective when ketoconazole fails or after relapse of infection following a response to ketoconazole. Fluconazole is not as effective therapy for blastomycosis based on the need for much higher doses than with itraconazole. In a patient with lifethreatening or central nervous system blastomycosis, amphotericin B should be given.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0882-0546
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
263-7
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Therapy of blastomycosis.
pubmed:affiliation
Dept of Medicine, University of Arkansas Center for Medical Sciences, Little Rock, USA.
pubmed:publicationType
Journal Article, Review