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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1997-10-30
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pubmed:abstractText |
We studied relationships between anti-ganglioside antibodies and the clinical characteristics of Guillain-Barré syndrome (GBS) using multivariate analysis. Serum anti-ganglioside antibodies were measured by enzyme-linked immunosorbent assay (ELISA) in 42 GBS patients and 47 controls. Relationships between antibodies and 15 clinical characteristics were analyzed using a logistic model. Anti-GM1 antibodies were significantly infrequent in patients with objective sensory disturbance (immunoglobulin G (IgG), p < 0.05, odds ratio = 0.094; immunoglobulin M (IgM), p < 0.01, odds ratio = 0.032) and frequent in patients with prodromal diarrhea (IgG, p < 0.05, odds ratio = 5.759; IgM, p < 0.05, odds ratio = 16.28). The combination of anti-GM1 and anti-GD1b antibodies was frequent in patients with prodromal diarrhea (IgG, p < 0.01, odds ratio = 9.667; IgM, p < 0.01, odds ratio = 14.50). IgG anti-GQ1b antibodies were extremely frequent in patients with ophthalmoplegia (p < 0.01, odds ratio = 102.3), and infrequent in patients with objective sensory disturbance (p < 0.05, odds ratio = 0.023).
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/G(M1) Ganglioside,
http://linkedlifedata.com/resource/pubmed/chemical/Gangliosides,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin M
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0918-2918
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
607-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9313102-Adolescent,
pubmed-meshheading:9313102-Adult,
pubmed-meshheading:9313102-Aged,
pubmed-meshheading:9313102-Antibodies,
pubmed-meshheading:9313102-Child,
pubmed-meshheading:9313102-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9313102-Female,
pubmed-meshheading:9313102-G(M1) Ganglioside,
pubmed-meshheading:9313102-Gangliosides,
pubmed-meshheading:9313102-Humans,
pubmed-meshheading:9313102-Immunoglobulin G,
pubmed-meshheading:9313102-Immunoglobulin M,
pubmed-meshheading:9313102-Male,
pubmed-meshheading:9313102-Middle Aged,
pubmed-meshheading:9313102-Polyradiculoneuropathy
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pubmed:year |
1997
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pubmed:articleTitle |
Relationships between anti-ganglioside antibodies and clinical characteristics of Guillain-Barré syndrome.
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pubmed:affiliation |
Department of Neurology, Kitasato University East Hospital, Sagamihara, Kanagawa.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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