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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8-9
|
pubmed:dateCreated |
1978-1-27
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pubmed:abstractText |
31 families with at least two psoriatic members, including sometimes three generations (4 families) have been studied looking for HL-A markers. They include 80 affected (45 females, 35 males) and 75 healthy persons. BW 17 has been found present in 58 p. 100 of the unrelated patients, versus 7 p. 100 only in the normal population (p less than 10-9). Relative risk (R.R.) for the people bearing BW 17 is 38.34. Increase of B 13 is slight and non significant. BW 16, BW 37, BW 27 are within normal range. B 12 (R.R. :0.36) seems to have a protecting effect. B 8, B 14 are also decreased. Study of way of genetic transmission favours existence of a dominant gene of susceptibility frequently associated with BW 17 and particularly with haplotype A 1, BW 17. But other genetic or environmental factors may also play a role.
|
pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0151-9638
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
525-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:931305-Adolescent,
pubmed-meshheading:931305-Adult,
pubmed-meshheading:931305-Child,
pubmed-meshheading:931305-Child, Preschool,
pubmed-meshheading:931305-France,
pubmed-meshheading:931305-Genes, Dominant,
pubmed-meshheading:931305-Genotype,
pubmed-meshheading:931305-HLA Antigens,
pubmed-meshheading:931305-Humans,
pubmed-meshheading:931305-Infant,
pubmed-meshheading:931305-Male,
pubmed-meshheading:931305-Pedigree,
pubmed-meshheading:931305-Phenotype,
pubmed-meshheading:931305-Psoriasis
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pubmed:articleTitle |
[HL-A system in psoriasis; study of 31 families (author's transl)].
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pubmed:publicationType |
Journal Article,
English Abstract
|