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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-11-20
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pubmed:abstractText |
Generalized disruption of arterial wall morphological changes in patients harboring cerebral aneurysms has been documented; however, little is known regarding the pathogenesis of these changes. To explore the role of the elastolytic gelatinase, matrix metalloproteinase-9 (MMP-9), levels of this enzyme in the wall of intracranial aneurysms were compared with those in both intracranial and extracranial arteries. The tissue levels of its major inhibitor, tissue inhibitor of metalloproteinase (TIMP), were measured in these tissues as well. The activity of MMP-9 in plasma was also evaluated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0148-396X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
642-66; discussion 646-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9310982-Aneurysm, Ruptured,
pubmed-meshheading:9310982-Biological Markers,
pubmed-meshheading:9310982-Cerebral Arteries,
pubmed-meshheading:9310982-Cohort Studies,
pubmed-meshheading:9310982-Collagenases,
pubmed-meshheading:9310982-Craniotomy,
pubmed-meshheading:9310982-Humans,
pubmed-meshheading:9310982-Intracranial Aneurysm,
pubmed-meshheading:9310982-Matrix Metalloproteinase 9,
pubmed-meshheading:9310982-Reference Values,
pubmed-meshheading:9310982-Temporal Arteries,
pubmed-meshheading:9310982-Tissue Inhibitor of Metalloproteinases
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pubmed:year |
1997
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pubmed:articleTitle |
Matrix metalloproteinase-9 in cerebral aneurysms.
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pubmed:affiliation |
Department of Neurological Surgery, Columbia University, College of Physicians and Surgeons, New York, New York, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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