Linked Life Data

930564

Source:http://linkedlifedata.com/resource/pubmed/id/930564

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1978-1-27
pubmed:abstractText
A recently recognised progressive disorder of central myelin in Dalmatian dogs is described. The disease is probably transmitted by autosomal recessive inheritance. The symptoms started at the age of 3-6 months and were dominated by visual deficiency and/or progressive locomotive abnormalities. Pathologically, the most consistent lesions were found bilaterally in the region of the centrum semiovale. The optic nerves were also frequently affected, the basal ganglia and spinal cord were affected infrequently. The main lesions were confined to myelin, while axons and nerve cells were spared, particularly in the early stages of the lesions. Numerous phagocytes were observed which contained engulfed myelin and other lipid breakdown products. Ultrastructurally and histochemically the disease differs from previously described types of leucodystrophy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0001-6322
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-9
pubmed:dateRevised
2007-11-9
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Hereditary "cavitating" leucodystrophy in Dalmation dogs. Light and electron microscopic studies.
pubmed:publicationType
Journal Article