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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-10-10
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pubmed:abstractText |
MSP-1 of Plasmodium falciparum induces strong proliferative T cell responses even in malaria-nonexposed individuals. Epitopes recognized by malaria-nonimmune T cells have not been identified, and immunological mechanisms inducing such T cell responses remain to be uncovered. MSP-1 is a vaccine candidate, and it should be understood whether those epitopes have any roles in MSP-1-mediated protective immunity. The T epitopes-inducing malaria-naive T cell response was analyzed in the hope of understanding the underlying mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1018-2438
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9303326-Amino Acid Sequence,
pubmed-meshheading:9303326-Animals,
pubmed-meshheading:9303326-Antigens, Protozoan,
pubmed-meshheading:9303326-Cell Line,
pubmed-meshheading:9303326-Cross Reactions,
pubmed-meshheading:9303326-Epitopes,
pubmed-meshheading:9303326-HLA-DR Antigens,
pubmed-meshheading:9303326-Humans,
pubmed-meshheading:9303326-Lymphocyte Activation,
pubmed-meshheading:9303326-Malaria, Falciparum,
pubmed-meshheading:9303326-Merozoite Surface Protein 1,
pubmed-meshheading:9303326-Molecular Sequence Data,
pubmed-meshheading:9303326-Peptide Fragments,
pubmed-meshheading:9303326-Plasmodium falciparum,
pubmed-meshheading:9303326-Protein Precursors,
pubmed-meshheading:9303326-Protozoan Proteins,
pubmed-meshheading:9303326-Sequence Homology, Amino Acid,
pubmed-meshheading:9303326-T-Lymphocytes
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pubmed:year |
1997
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pubmed:articleTitle |
Epitope analysis of human T-cell response to MSP-1 of Plasmodium falciparum in malaria-nonexposed individuals.
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pubmed:affiliation |
Department of Medical Zoology, Nagoya City University Medical School, Nagoya, Japan. nohta@med.nagoya-cu.ac.jp
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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