Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
32
pubmed:dateCreated
1997-9-18
pubmed:abstractText
The revised European-American Classification of Lymphoid Neoplasms (REAL), proposed by the International Lymphoma Study Group, contains molecular genetic data which may characterize a given lymphoma entity. In this recent review, the molecular genetic alterations integrated into the diagnostic procedure of lymphomas are discussed. Based on our recent knowledge the rearrangements of bcl-1, bcl-2, bcl-6, anaplastic lymphoma kinase and c-myc genes are associated with mantle cell, diffuse large B-cell, anaplastic large cell and Burkitt's lymphomas, respectively. The integration of the relevant molecular data in the evaluation of objective diagnoses and therefore specific and successful therapies. Furthermore, the knowledge of the molecular event associated with lymphomas helps to better understand tumor development and biology.
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0030-6002
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
138
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1999-2003
pubmed:dateRevised
2009-10-21
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[The role of genetic studies in the diagnosis and classification of non-Hodgkin lymphoma].
pubmed:affiliation
Pécsi Orvostudományi Egyetem, Pathologiai Intézet, Pécs.
pubmed:publicationType
Journal Article, English Abstract