Linked Life Data

9294374

Source:http://linkedlifedata.com/resource/pubmed/id/9294374

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pubmed-article:9294374pubmed:abstractTextDisturbances in the orbital prefrontal cortex and its ventral striatal target fields have been identified in neuroimaging studies of obsessive-compulsive disorder (OCD). In animal models and studies of patients with lesions to this brain circuitry, a selective disturbance in the ability to suppress responses to irrelevant stimuli has been demonstrated. Such a deficit in response suppression might underlie the apparent inhibitory deficit suggested by the symptoms of OCD. To date, little direct evidence of such a deficit has been reported. Further, although OCD commonly emerges during childhood or adolescence, few studies have examined psychotropic-naive pediatric patients near the onset of illness to find the possible role of atypical developmental processes in this disorder.lld:pubmed
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pubmed-article:9294374pubmed:articleTitleOculomotor response inhibition abnormalities in pediatric obsessive-compulsive disorder.lld:pubmed
pubmed-article:9294374pubmed:affiliationDepartment of Psychiatry, University of Pittsburgh Medical Center, Pa., USA. Drosen@med.wayne.edulld:pubmed
pubmed-article:9294374pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9294374pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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