Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-10-1
pubmed:abstractText
The distribution of fibroblast growth factor (FGF) and of the mRNA for its receptor encoded by MFR1 were examined in the testis of the medaka, Oryzias latipes. FGF was detected in the region of somatic cells, especially in Sertoli cells in the matured testis by immunostaining. The staining was also detected in some of the type A spermatogonia. The distribution of FGF in the testis of the fry, in which spermatogenesis had not been initiated, was different from that in the adult. Signals of mRNA were observed in the same region as FGF in the matured testis. Staining was also detected in the testis of the fry in which spermatogenesis had been initiated. Therefore, the role of FGF in the testis of the fry in the early developmental stages may be different from that of the adult: These results indicate that FGF regulates the activation of somatic cells in the testis through the MFR1 receptor, and that it might play a significant role in the initiation and the progression of spermatogenesis in the testis of O. latipes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-104X
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
279
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
177-84
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Distributions of fibroblast growth factor and the mRNA for its receptor, MFR1, in the developing testis of the medaka, Oryzias latipes.
pubmed:affiliation
Department of Biology, Faculty of Science, Yamagata University, Japan. watan@sci.kj.yamagata-u.ac.jp
pubmed:publicationType
Journal Article