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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1997-12-5
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pubmed:abstractText |
We report a 30 years old woman with sporadic poliglandular autoimmune syndrome type II, first seen with an insulin-dependent diabetes mellitus and a Graves-Basedow disease that became spontaneously hypothyroid with positive antimicrosomal antibodies. Six years later she presented with persistent vomiting and a remarkable reduction in insulin requirements. She had low basal and stimulated-cortisol levels and the diagnosis of severe adrenal failure was reached. A CT scan showed normal adrenal glands, she did not have cutaneous hyperpigmentation nor evidences of mineralocorticoid deficit. A selective autoimmune damage of the fascicular zone was assumed but a selective damage of ACTH producing pituitary cells cannot be discarded. The importance of investigating adrenal function in cases of unexplained reduction of insulin requirements is emphasized.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0034-9887
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1374-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:9293104-Addison Disease,
pubmed-meshheading:9293104-Adult,
pubmed-meshheading:9293104-Diabetes Complications,
pubmed-meshheading:9293104-Diabetes Mellitus,
pubmed-meshheading:9293104-Female,
pubmed-meshheading:9293104-Graves Disease,
pubmed-meshheading:9293104-Humans,
pubmed-meshheading:9293104-Hypoglycemic Agents,
pubmed-meshheading:9293104-Insulin,
pubmed-meshheading:9293104-Thyroiditis, Autoimmune
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pubmed:year |
1996
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pubmed:articleTitle |
[Asymptomatic Addison disease: cause of striking reduction of insulin requirements in a patient with diabetes, Hashimoto thyroiditis and Basedow disease].
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pubmed:affiliation |
Servicio de Medicina y Laboratorio Central, Hospital Regional de Talca, Chile.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|