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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-10-14
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pubmed:abstractText |
This paper describes an extension of linear mixed models to allow for heterogeneous within-cluster variances in the analysis of clustered data. Unbiased estimating equations based on quasilikelihood/pseudolikelihood and method of moments are introduced and are shown to give consistent estimators of the regression coefficients, variance components, and heterogeneity parameter under regularity conditions. Cluster-specific random effects and variances are predicted by the posterior modes. The method is illustrated through an analysis of menstrual diary data and its properties are evaluated in a simulation study.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-341X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
910-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9290222-Adolescent,
pubmed-meshheading:9290222-Adult,
pubmed-meshheading:9290222-Analysis of Variance,
pubmed-meshheading:9290222-Biometry,
pubmed-meshheading:9290222-Cluster Analysis,
pubmed-meshheading:9290222-Female,
pubmed-meshheading:9290222-Humans,
pubmed-meshheading:9290222-Medical Records,
pubmed-meshheading:9290222-Menstruation,
pubmed-meshheading:9290222-Models, Statistical,
pubmed-meshheading:9290222-Periodicity
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pubmed:year |
1997
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pubmed:articleTitle |
Linear mixed models with heterogeneous within-cluster variances.
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pubmed:affiliation |
Department of Biostatistics, University of Michigan, Ann Arbor 48109, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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