|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
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|
pubmed:dateCreated |
1997-10-9
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|
pubmed:abstractText |
Symptoms of acute radiation enteritis (ARE), dominated by diarrhea, occur in more than 70% of patients receiving pelvic irradiation. Eicosanoids and free radicals release have been implicated in the pathogenesis. Mesalazine (5-ASA) is a potent inhibitor of their synthesis in the mucosa and could therefore be of some interest in preventing ARE.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
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|
pubmed:issn |
0167-8140
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
44
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
59-63
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9288859-Acute Disease,
pubmed-meshheading:9288859-Adult,
pubmed-meshheading:9288859-Aged,
pubmed-meshheading:9288859-Aminosalicylic Acids,
pubmed-meshheading:9288859-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:9288859-Diarrhea,
pubmed-meshheading:9288859-Double-Blind Method,
pubmed-meshheading:9288859-Enteritis,
pubmed-meshheading:9288859-Female,
pubmed-meshheading:9288859-Humans,
pubmed-meshheading:9288859-Male,
pubmed-meshheading:9288859-Mesalamine,
pubmed-meshheading:9288859-Middle Aged,
pubmed-meshheading:9288859-Pelvis,
pubmed-meshheading:9288859-Radiation Injuries,
pubmed-meshheading:9288859-Radiotherapy
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|
pubmed:year |
1997
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|
pubmed:articleTitle |
A randomized double blind placebo controlled multicenter study of mesalazine for the prevention of acute radiation enteritis.
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|
pubmed:affiliation |
Centre de Recherche et de Lutte Contre le Cancer, Institut Paoli-Calmettes, Marseille, France.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Multicenter Study
|
