Linked Life Data

9288122

Source:http://linkedlifedata.com/resource/pubmed/id/9288122

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pubmed-article:9288122pubmed:abstractTextOlomoucine and roscovitine are novel compounds that are designed to inhibit cyclin-dependent kinases (e.g., Cdk2 and cdc2). Cdks regulate progression through key checkpoints of the cell cycle. The purpose of this study was to determine (1) whether olomoucine and roscovitine inhibit Cdk2 and cdc2 kinase activities of the human gastric cancer cell line SIIA and (2) whether olomoucine and roscovitine block cell proliferation and cell cycle progression.lld:pubmed
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pubmed-article:9288122pubmed:pagination187-94; discussion 194-5lld:pubmed
pubmed-article:9288122pubmed:dateRevised2009-11-19lld:pubmed
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pubmed-article:9288122pubmed:articleTitleCyclin-dependent kinase inhibitors block proliferation of human gastric cancer cells.lld:pubmed
pubmed-article:9288122pubmed:affiliationDepartment of Surgery, University of Texas Medical Branch, Galveston 77555-0542, USA.lld:pubmed
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